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Registros recuperados: 21
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Association studies between -1185A/G von Willebrand factor gene polymorphism and coronary artery disease BJMBR
Simon,D.; Paludo,C.A.; Ghisleni,G.C.; Manfroi,W.C.; Roisenberg,I..
High levels of von Willebrand factor (vWF) have been associated with cardiovascular disease. The A allele of the -1185A/G polymorphism in the 5'-regulatory region of the vWF gene was associated with the highest plasma vWF levels in a normal population. To examine the association between -1185A/G polymorphism and coronary artery disease (CAD), 173 Brazilian Caucasian subjects submitted to coronary angiography were studied. Of these, 57 (33%) had normal coronary arteries (control group) and 116 (67%) had CAD (patient group). Plasma vWF levels were higher in patients (145 U/dl) than in controls (130 U/dl), but the differences were significant only for O blood group subjects. Polymerase chain reaction amplification of the 864-bp vWF promoter region followed by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Von Willebrand factor; Coronary artery disease; DNA polymorphisms; Risk factor.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600005
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Bovine Vaccinia in dairy cattle and suspicion of vesicular disease on milkers in Brazil Ciência Rural
Silva,Thaís Garcia da; Lima,Michele dos Santos; Castro,Alessandra Marnie Martins Gomes de; Martins,Maira de Souza Nunes; Castiglioni,Vivian Cardoso; Fava,Claudia Del; Okuda,Liria Hiromi; Pituco,Edviges Maristela.
ABSTRACT: Bovine vaccinia (BV) is a vesicular disease induced by the Vaccinia virus (VACV) that affects milk production and is an occupational zoonosis. This research had the following objectives: (i) detection of VACV by qPCR in cattle with clinical suspicion of vesicular disease; (ii) symptoms characterization in animals and milkers with clinical suspicion of the disease and virus detection in humans; and (iii) identification of risk factors for infections of VACV in herds from several Brazilian states. A total of 471 bovine epithelial samples from dairy farms, in 15 Brazilian states, were evaluated between 2007 and 2012. The samples were tested by quantitative PCR (qPCR) using SYBR Green® reagents, validated with a lower limit of detection of 100...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Orthopoxvirus; Poxviridae; Quantitative PCR; Risk factor; VACV; Zoonosis.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000500451
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Comparison between the jugular and subclavian vein as insertion site for central venous catheters: microbiological aspects and risk factors for colonization and infection BJID
Sadoyama,Geraldo; Gontijo Filho,Paulo Pinto.
Bacterial counts were made of catheter insertion site and of catheter tips to help determine risk factors associated with catheterization of the jugular and subclavian veins. Among the 116 patients included in this study, 69% had central venous catheters (CVC) in the subclavian vein. Seven or more days catheterization (p=0.001) and >3 invasive devices (p=0.01) were infection risk factors associated with catheterization of the jugular vein. More than half of the patients presented high colony counts at the insertion site (>200 CFU/20 cm²) and 27% of the catheter tips were contaminated. The risk factors associated with contaminated catheter tips were >14 days hospital stay (p=0.02), >7 days catheterization (p=0.01) and antibiotic therapy...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CVC; Risk factor; CR-BSI; ORSA; ORCoNS.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000200008
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Estimating Dynamic Risk Factors for Pathogen Transmission Using Community-Level Bird Census Data at the Wildlife/Domestic Interface Ecology and Society
Caron, Alexandre; UPR AGIRs, Department ES, Cirad, Harare Zimbabwe; UPR AGIRs, Department ES, Cirad, Montpellier France; Mammal Research Institute, Department of Entomology and Zoology, University of Pretoria, Pretoria, South Africa; alexandre.caron@cirad.fr; de Garine-Wichatitsky, Michel; UPR AGIRs, Deparmtent ES, Cirad, Harare, Zimbabwe; UPR AGIRs, Department ES, Cirad, Montpellier, France; degarine@cirad.fr; Gaidet, Nicolas; UPR AGIRs, Department ES, Cirad, Montpellier, France; nicolas.gaidet-drapier@cirad.fr; Chiweshe, Ngoni; UPR AGIRs, Department ES, Cirad, Harare, Zimbabwe; chiweshen@yahoo.co.uk; Cumming, Graeme S; Percy Fitz-Patrick Institute, DST/NRF Center of Excellence, University of Cape Town; Graeme.Cumming@uct.ac.za.
Tipo: Peer-Reviewed Reports Palavras-chave: Avian influenza; Bridge species; Community ecology; Risk factor; Wild/domestic interface.
Ano: 2010
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Genetic and non-genetic effects on calf vigor at birth and preweaning mortality in Nellore calves R. Bras. Zootec.
Schmidek,Anita; Costa,Mateus José Rodrigues Paranhos da; Mercadante,Maria Eugênia Zerlotti; Toledo,Luciandra Macedo de; Cyrillo,Joslaine Noely dos Santos Gonçalves; Branco,Renata Helena.
The objective of the present study was to evaluate the genetic and non-genetic effects that influence vigor at birth and preweaning mortality in Nellore calves. A total of 11,727 records of births that occurred between 1978 and 2006, offspring of 363 sires, were analyzed. Poor calf vigor at birth (VB) and preweaning mortality divided into stillbirth (SB), early mortality (EM) and total mortality (TM) were analyzed as binary variables. Generalized linear models were used for the evaluation of non-genetic effects and generalized linear mixed models for genetic effects (sire and animal models). The incidences were 4.75% for VB, 2.66% for SB, 5.28% for EM, and 7.99% for TM. Birth weight was the effect that most influenced the traits studied. Calves weighing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Animal welfare; Beef cattle; Calf mortality; Genetic improvement; Risk factor.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982013000600006
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HBV epidemiology and genetic diversity in an area of high prevalence of hepatitis B in southern Brazil BJID
Paoli,Juliana de; Wortmann,André Castagna; Klein,Mirelli Gabardo; Pereira,Vagner Reinaldo Zingalli Bueno; Cirolini,Adriana Maria; Godoy,Bibiane Armiliato de; Fagundes,Nelson Jurandi Rosa; Wolf,Jonas Michel; Lunge,Vagner Ricardo; Simon,Daniel.
ABSTRACT Background Hepatitis B virus (HBV) infection is a major public health problem in Brazil. HBV endemicity is usually moderate to low according to geographic regions, and high prevalence of this virus has been reported in people of some specific Brazilian counties, including those with a strong influence of Italian colonization in southern Brazil. Analysis of HBV diversity and identification of the main risk factors to HBV infection are necessary to understand hepatitis B epidemiology in these high prevalence regions in southern Brazil. Objective To investigate epidemiological characteristics and HBV genotypes and subgenotypes circulating in a specific city with high HBV prevalence. Methods A cross-sectional study was performed with 102 HBV...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HBV infection; Epidemiology; HBV genotypes; Risk factor; Transmission; Cross-sectional studies.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400294
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HFE gene mutations in coronary atherothrombotic disease BJMBR
Calado,R.T.; Franco,R.F.; Pazin-Filho,A.; Simões,M.V.; Marin-Neto,J.A.; Zago,M.A..
Although iron can catalyze the production of free radicals involved in LDL lipid peroxidation, the contribution of iron overload to atherosclerosis remains controversial. The description of two mutations in the HFE gene (Cys282Tyr and His63Asp) related to hereditary hemochromatosis provides an opportunity to address the question of the association between iron overload and atherosclerosis. We investigated the prevalence of HFE mutations in 160 survivors of myocardial infarction with angiographically demonstrated severe coronary atherosclerotic disease, and in 160 age-, gender- and race-matched healthy control subjects. PCR amplification of genomic DNA followed by RsaI and BclI restriction enzyme digestion was used to determine the genotypes. The frequency...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hemochromatosis; HFE gene; Atherosclerosis; Myocardial infarction; Risk factor.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300007
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High Postprandial Triglycerides Serum Levels: Is Obesity a Good Predictor? Anais da ABC (AABC)
NOGAROTO,VIVIANE; RODRIGUES,MARCOS R.S.; VICARI,MARCELO R.; ALMEIDA,MARA C. DE; MILLÉO,FÁBIO Q.; SANTOS,FÁBIO A. DOS; ARTONI,ROBERTO F..
The aim of this study was to analyze the correlation between triglyceride (TG) serum levels in obese and non-obese patients in a simulated postprandial state. Both groups showed TG levels < 150 mg/dL when fasting. After 12 h fasting, the subjects ingested a lipid overload diet and blood samples were collected. The variation between fasting and the postprandial TG peak levels were analyzed. The peak of postprandial TG levels occurred 4 h after the lipid overload in both groups. When the subjects were not fasting, the majority of non-obese subjects remained within the range of normal TG values, but the values for the obese group remained elevated. There was a significant correlation between Body Mass Index (BMI) and TG at each time point until 2 h after...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Body mass index; Lipid metabolism; Risk factor; ROC curve.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100437
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High prevalence of hepatitis C infection in a Brazilian prison: identification of risk factors for infection BJID
Guimarães,Thaís; Granato,Celso F. H.; Varella,Drauzio; Ferraz,Maria Lúcia G.; Castelo,Adauto; Kallás,Esper Georges.
Hepatitis C virus (HCV) causes infectious hepatitis worldwide. It is transmitted mainly by blood products and sharing of intravenous paraphernalia during illicit drug use. High prevalence rates have been described among specific groups considered to be at higher risk for HCV infection, including prison inmates. The objectives of this study were: to determine the HCV seroprevalence among inmates of Casa de Detenção de São Paulo; to identify risk factors for HCV infection; and to compare the seroprevalence of HCV to other blood borne or sexually transmitted diseases. From December, 1993, to January, 1994, a total of 779 inmates were interviewed to collect information on sociodemographic status, sexual behavior, and past experience with illicit drugs. Blood...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HCV; Seroprevalence; Prison; Risk factor.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000300002
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Identification and antimicrobial susceptibility of Staphylococcus from home-treated peritoneal dialysis patients J. Venom. Anim. Toxins incl. Trop. Dis.
Batalha,JEN; Cunha,MLRS; Montelli,AC; Barreti,P; Caramori,JCT.
Staphylococcus aureus is the main agent of infections during peritoneal dialysis (PD). The presence of S. aureus in the nasal cavity has been extensively studied and suggested as a risk factor of dialysis-related infections, whereas coagulase-negative Staphylococcus (CNS) species are frequently considered part of the normal human microbiota. The aim of this study was to identify Staphylococcus in the nasal cavity, pericatheter skin and peritoneal effluent from PD patients, as well as to evaluate the antimicrobial activity evolution in vitro. Thirty-two chronic PD patients were observed during 12 months and had nasal and pericatheter skin samples collected for culture. When peritonitis was detected, samples were also collected from the peritoneal effluent...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Peritoneal dialysis (PD); Peritonitis; Risk factor; Staphylococcus; Coagulase-negative Staphylococcus (CNS).
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200005
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Identifying and controlling a multiresistant pseudomonas aeruginosa outbreak in a latin-american cancer centre and its associated risk factors BJID
Cortes,Jorge Alberto; Cuervo,Sonia Isabel; Urdaneta,Ana María; Potdevin,Guillermo; Arroyo,Patricia; Bermúdez,Diana; Correa,Adriana; Villegas,María Virginia.
Pseudomonas aeruginosa is an important and frightening microorganism for patients suffering from cancer. Multiresistant P. aeruginosa (MRPA) may appear as a consequence of exposure to multiple antibiotics or from a breakdown in infection control practices. This article reports an MRPA outbreak in a cancer treatment centre and the consequent case control study. Mechanical ventilation was identified as being the main risk factor for developing MRPA colonisation or infection; molecular analysis confirmed the outbreak. A multifaceted strategy was adopted, involving reinforcing hand-washing practices, contact isolation, antibiotic restriction and suction devices for mechanically-ventilated patients. MRPA was controlled and the outbreak ended. Such strategy may...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; Epidemiology; Multiple drug resistance; Bacteria; Risk factor.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200005
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Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil BJID
Nagaya,Leonardo Hideto; Salles,Mauro José Costa; Takikawa,Lucas Sadawo Chagas; Fregoneze,Marcelo; Doneux,Pedro; Silva,Luciana Andrade da; Sella,Guilherme do Val; Miyazaki,Alberto Naoki; Checchia,Sergio Luiz.
ABSTRACT Purposes: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following Shoulder arthroplasty remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after Shoulder arthroplasty. Methods: An unmatched case-control study was conducted to describe the prevalence, clinical and microbiological findings, and to evaluate patient and surgical risk factors for prosthetic shoulder infection (PSI), among 158...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Orthopedic infection; Hemiarthroplasty; Total shoulder arthroplasty; American Society of Anesthesiologists score; Risk factor; Pseudomonas aeruginosa.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600613
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Ischemia and fibrosis: the risk mechanisms of hypertensive heart disease BJMBR
Frohlich,E.D..
Mechanisms underlying risk associated with hypertensive heart disease (HHD) and left ventricular hypertrophy (LVH) are discussed in this report and provide a rationale for understanding this very common and important cause of death from hypertension and its complications. Emphasized are impaired coronary hemodynamics, endothelial dysfunction, and ventricular fibrosis from increased collagen deposition intramurally and perivascularly. Each is exacerbated by aging and, perhaps, also by increased dietary salt intake. These functional and structural changes promote further endothelial dysfunction, altered coronary hemodynamics, and diastolic as well as systolic ventricular contractile function in HHD. The clinical endpoints of HHD include angina pectoris (with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Left ventricular hypertrophy; LVH; Risk factor; Myocardial ischemia; Ventricular fibrosis.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600010
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Mastitis in the transition period: identification of potential blood markers Arq. Bras. Med. Vet. Zootec.
Santos,K.R.; Souza,F.N.; Blagitz,M.G.; Batista,C.F.; Bertagnon,H.G.; Gomes,R.C.; Molinari,P.C.C.; Diniz,S.A.; Silva,M.X.; Haddad,J.P.A.; Heinemann,M.B.; Libera,A.M.M.P.D..
ABSTRACT This study identified potential blood markers associated with mastitis in dairy cows under different dry therapies during the transition period, using a logistic regression model. Thirty-four Holstein dairy cows were divided into three groups: untreated controls (13 cows, 42 quarters); animals that received an antimicrobial at drying-off (10 cows, 40 quarters); and animals that were administered an internal teat sealant at drying-off (11 cow, 44 quarters). Blood and quarter milk samples were collected 60 days before the expected day of calving, on the day of calving, and three, seven, 15, 21, and 30 days after calving. Milk samples were submitted for bacteriological analysis and somatic cell count. Blood samples were collected for analyses of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Intramammary infection; Risk factor; Drying-off; Periparturient period; Metabolism.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000401120
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Morphological Distinguish of Rupture Status between Sidewall and Bifurcation Cerebral Aneurysms International Journal of Morphology
Qiu,Tianlun; Xing,Haiyan.
We suspect that morphological change of two types of aneurysms in ruptured and unruptured aneurysms are distinguishing because of different location and haemodynamics. So it is necessary to discuss sidewall and bifurcation type aneurysms in ruptured and unruptured state respectively. We used 209 consecutive aneurysms (144 ruptured, 65 bifurcation type) to assess the following parameters in 3D: maximum diameter (Dmax), maximum height (Hmax), aspect ratio (AR), size ratio (SR), height/width ratio (HW), bottleneck factor (BNF, width/neck) and inflow angle (IR). These aneurysms were divided into four groups by whether ruptured and sidewall or bifurcation. 4 groups were pairwise compared by univariate analysis and some parameters with significant variation were...
Tipo: Journal article Palavras-chave: Intracranial aneurysm; Cerebral aneurysm; Risk factor; Subarachnoid hemorrhage; Morphology; Rupture.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300059
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Percent body fat is a better predictor of cardiovascular risk factors than body mass index BJMBR
Zeng,Qiang; Dong,Sheng-Yong; Sun,Xiao-Nan; Xie,Jing; Cui,Yi.
The objective of the present study was to evaluate the predictive values of percent body fat (PBF) and body mass index (BMI) for cardiovascular risk factors, especially when PBF and BMI are conflicting. BMI was calculated by the standard formula and PBF was determined by bioelectrical impedance analysis. A total of 3859 ambulatory adult Han Chinese subjects (2173 males and 1686 females, age range: 18-85 years) without a history of cardiovascular diseases were recruited from February to September 2009. Based on BMI and PBF, they were classified into group 1 (normal BMI and PBF, N = 1961), group 2 (normal BMI, but abnormal PBF, N = 381), group 3 (abnormal BMI, but normal PBF, N = 681), and group 4 (abnormal BMI and PBF, N = 836). When age, gender, lifestyle,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Body composition; Body mass index; Cardiovascular disease; Risk factor; Percent body fat; Bioelectrical impedance.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700005
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Prevalence and Risk Factor Analysis of Bovine Hemoplasma Infection by Direct PCR in Eastern Hokkaido, Japan OAK
TAGAWA, Michihito; YBANEZ, Adrian P.; MATSUMOTO, Kotaro; YOKOYAMA, Naoaki; INOKUMA, Hisashi; 松本, 高太郎; 横山, 直明; 猪熊, 壽.
The prevalence and risk factors of 2 bovine hemoplasma species—Mycoplasma wenyonii (Mw) and “Candidatus Mycoplasma haemobos” (CMh)—were examined by direct PCR using whole blood samples collected from 343 cattle in Eastern Hokkaido, Japan. The sensitivity of the direct PCR assay was 10-fold higher than the standard PCR assay, detecting 5 copies of bovine hemoplasma DNA per reaction. An epidemiological survey of sampling location, living conditions, age and bovine leukemia virus antibody was performed to assess infection risk factors. The prevalence rates were 38.5% for Mw and 39.1% for CMh, respectively, with an overall prevalence rate of 64.7% for all bovine hemoplasma infections. Significant differences were found in sampling location, living conditions...
Palavras-chave: Bovine hemoplasma; Direct PCR; Japan; Risk factor.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3838
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[RETRACTED ARTICLE] Bovine Vaccinia in dairy cattle and suspicion of vesicular disease on milkers in Brazil Ciência Rural
Silva,Thaís Garcia da; Lima,Michele dos Santos; Castro,Alessandra Marnie Martins Gomes de; Martins,Maira de Souza Nunes; Castiglioni,Vivian Cardoso; Fava,Claudia Del; Okuda,Liria Hiromi; Pituco,Edviges Maristela.
ABSTRACT: Bovine vaccinia (BV) is a vesicular disease induced by the Vaccinia virus (VACV) that affects milk production and is an occupational zoonosis. This research had the following objectives: (i) detection of VACV by qPCR in cattle with clinical suspicion of vesicular disease; (ii) symptoms characterization in animals and milkers with clinical suspicion of the disease and virus detection in humans; and (iii) identification of risk factors for infections of VACV in herds from several Brazilian states. A total of 471 bovine epithelial samples from dairy farms, in 15 Brazilian states, were evaluated between 2007 and 2012. The samples were tested by quantitative PCR (qPCR) using SYBR Green® reagents, validated with a lower limit of detection of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Orthopoxvirus; Poxviridae; Quantitative PCR; Risk factor; VACV; Zoonosis.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000600455
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Risk factors for infection by Toxoplasma gondii in herds of goats in Ceará, Brazil Arq. Bras. Med. Vet. Zootec.
Cavalcante,A.C.R.; Carneiro,M.; Gouveia,A.M.G.; Pinheiro,R.R.; Vitor,R.W.A..
In order to identify possible risk factors for T. gondii infection in goat herds in Ceará, Brazil, 2362 serum samples were tested by ELISA. The serological prevalence was 25.1%. The risk factors identified for Toxoplasma gondii infection in goat herds were age, number of cats, use of wooden feeding troughs and absence of feeding troughs. Goats older than 37 months had 2.01 (CI 95%; 1.55 - 2.61) higher risk of infection than younger animals. Greater risk of infection was observed in farms with more than 10 cats (OR = 1.73; CI 95%; 1.01 - 3.33). The use of wooden feeding troughs represented a high probability of infection (OR = 7.81; CI 95%; 1.66 - 36.67). The lack of feeding troughs also represented a high probability of infection (OR = 5.50; CI 95%; 1.24 -...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goat; Prevalence; Toxoplasma gondii; Risk factor; Ceará.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000100006
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Risk factors for pan-resistant Pseudomonas aeruginosa bacteremia and the adequacy of antibiotic therapy BJID
Tuon,Felipe F.; Gortz,Lucas W.; Rocha,Jaime L..
INTRODUCTION: The aim of this study was to determine risk factors for acquiring carbapenemresistant Pseudomonas aeruginosa bacteremia (CR-PA) and factors associated with in-hospital mortality. METHODS: Seventy-seven cases of bacteremia caused by P. aeruginosa were evaluated in a hospital with high incidence of CR-PA. Clinical and laboratorial factors, and previous use of antibiotics were also evaluated. In one analysis, CR-PA and carbapenem-susceptible P. aeruginosa (CS-PA) bacteremia were compared. A second analysis compared patients who died with survivors. RESULTS: Among 77 P. aeruginosa bacteremia, 29 were caused by CR-PA. Admission to the intensive care unit, higher number of total leukocytes, and previous use of carbapenem were statistically...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; Imipenem; Meropenem; Antibiotic resistance; Risk factor.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000400007
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